The association between micronutrients and COVID-19 has been demonstrated in the review based on scientific evidence that showed the role of nutrients to strengthen the immune
system against the emerging infection caused by COVID-19.

The review emphasizes micronutrients’ role in the development and efficient functioning of the immune system, primarily the antiviral defense system.

Zinc plays a vital role in the maintenance and growth of adaptive and innate immune cells. Zinc deficiency results in immune
system dysfunction, which increases the susceptibility to infections and diseases.

Iron is a necessary nutrient and contributes substantially to the development of immunity.
Iron deficiency can impair host immunity, as various immune system cells need iron for their growth
and development

Vitamin C (ascorbic acid) is water-soluble is a powerful antioxidant. Its main function is related to immunity, and it has been shown to protect against various infections, including coronavirus infections. For example, vitamin C can improve the resistance of cultured chick embryos against avian coronavirus infections.

Copper is an essential trace dietary mineral present almost in all living organisms. Copper can boost the host’s immune system response against pathogens, exhibiting strong antibacterial, antifungal, antiviral and anti-inflammatory effects.

Review
“Effective Immune Functions of Micronutrients
against SARS-CoV-2″.
Kashaf Junaid, Hasan Ejaz, Abualgasim Elgaili Abdalla 1,2 , Khalid O. A. Abosalif, Muhammad Ikram Ullah, Humaira Yasmeen, Sonia Younas, Sanaa S. M. Hamam, Abdul Rehman.

“COVID-19: The Potential Role of Copper and N-acetylcysteine (NAC) in a Combination of Candidate Antiviral Treatments Against SARS-CoV-2”. ANDRI ANDREOU, SOFIA TRANTZA, DEMETRIOS FILIPPOU, NIKOLAOS SIPSAS and SOTIRIOS TSIODRAS.

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